Adapted from “NIH eRA Commons Items of Interest”
Updated Funding Opportunity Announcements (FOAs): NIH Institutes are continually evaluating and updating funding opportunities. Sometimes this results in having an FOA expire earlier than previously announced. It is good practice to revisit your FOAs within 30 days of the deadline to ensure you have the most recent information available. Pay special attention to the Related Notices and Key Date sections of the announcement.

For example, a new R13/U13 parent announcement has been issued (PA-12-212). This is a reissue of PA-10-071, which, if you look at the FOA, now says the following for expiration date: Expiration Date: June 27, 2012 (Original date: January 8, 2013). If you hadn’t checked the announcement, you would not have known until Grants.gov rejected the application. So don’t let your application be DOA because you are using an expired announcement.
Note: Researchers can also look for changes to FOAs in Notices at http://grants.nih.gov/grants/guide/index.html.